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EcoTox Knowledgebase (USA)

Toxic Chemicals Database

The ECOTOXicology knowledgebase (ECOTOX) is a searchable source for locating single chemical toxicity data for aquatic life, terrestrial plants and wildlife. The database includes more than 11,400 chemicals and their affects on more than 12,500 species. 

ECOTOX was created and is maintained by the U.S.EPA, Office of Research and Development (ORD), and the National Health and Environmental Effects Research Laboratory's (NHEERL's) Mid-Continent Ecology Division (MED).

ECOTOX integrates three previously independent databases - AQUIRE, PHYTOTOX, and TERRETOX - into a unique system which includes toxicity data derived predominately from the peer-reviewed literature, for aquatic life, terrestrial plants, and terrestrial wildlife, respectively.

If you know the exact search term(s) you are looking for, you can head straight to the Search page. However, if you’d like to explore the ECOTOX system and its available search parameters, use the Explore page.

ECOTOX is the primary source of toxicity data used by EPA regulatory programs to develop chemical assessments to meet requirements for the Clean Water Act (CWA), Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). ECOTOX is EPA’s premier publicly available application providing environmental chemical toxicity data to assess the effects that chemical exposures have on aquatic life, terrestrial plants, and wildlife.